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Subject:
From:
Tony Cundell <[log in to unmask]>
Reply To:
The Pharmaceutical Microbiology Forum Email List <[log in to unmask]>
Date:
Sat, 18 Mar 2023 00:51:19 -0400
Content-Type:
text/plain
Parts/Attachments:
text/plain (1376 lines)
Don,

I support your comprehensive analysis and conclusion.

I believe the manufacturer and the FDA should be more vigorous in their
investigations.

Tony

On Fri, Mar 17, 2023 at 6:59 PM Donald English <[log in to unmask]>
wrote:

> Dear Tony,
>
> Regarding the composition of Atovaquone Oral Suspension, I looked at
> the ingredients of this formulation to see whether they could be used
> as a microbial nutrient for spore germination:
>
> Atovaquone – is an anti-infective agent.  Highly unlikely that it
> would be able to support the germination of Bacillus cereus spores.
>
> Xanthan Gum – is an extracellular polysaccharide gum that is produced
> when glucose or sucrose is fermented by Xanthomonas campestris (A
> Gram-negative bacilli).  It is used in formulations either as a
> binder, thickener, stabilizer, or emulsifier at a concentration
> between 0.1 and 1.0%.  However, it does have antimicrobial activity
> against S. aureus (MIC Value of 0.63 mg/ml).  In the past, I have
> found batches of it to be contaminated with low levels of
> Gram-negative bacilli.  In addition, Xanthan gum can decrease the
> water activity of a formulation.  However, I have not found any
> scientific literature references indicating that it can be used as a
> microbial nutrient for growth.
>
> Poloxamer 188 – is a nonionic linear copolymer surfactant and it does
> have some antimicrobial activity.  I have seen it be used at a usage
> concentration of 0.1 to 0.3% in a product formulation.  It has
> antimicrobial activity against M. avium and Streptococcus coeliola,
> but it does not have antimicrobial activity against S. aureus, Ps.
> aeruginosa, M. luteus, E. coli, and etc.  It is a surfactant that is
> manufactured by using a high temperature and pressures by using the
> following ingredients of Propylene oxide, ethylene oxide and Propylene
> glycol.  Highly unlikely that it could be used as a microbial nutrient
> for the germination of Bacillus cereus spores.
>
> Saccharin, Sodium – is an artificial sweetener that has no nutritional
> value.  Not a microbial nutrient.
>
> Benzyl alcohol – preservative.  Not a microbial nutrient.
>
> Based upon the overall composition of this product formulation, I find
> it highly likely that Bacillus cereus spores would be able to
> germinate in this formulation due to the absence of microbial
> nutrients in the current formulation.  Because Benzyl alcohol is
> inactive against spores, I do believe that Bacillus cereus spores
> would be able to survive in this formulation.
>
> Don
>
> Donald J. English Microbiological Quality Consulting LLC
> Florham Park, New Jersey 07932
>
>
>
> On Fri, Mar 17, 2023 at 2:10 PM Tony Cundell <[log in to unmask]>
> wrote:
> >
> > Robert,
> >
> > As a multiple-use oral suspension I assume it passes the USP <51>
> > requirements. More important than the method is the challenge-organism
> > selection.
> >
> > Tony
> >
> > On Fri, Mar 17, 2023 at 1:22 PM Robert Pritchett <
> > [log in to unmask]> wrote:
> >
> > > Hello all,
> > >
> > > I've been following this discussion with great interest. I would very,
> > > very much like to see the AET data for this product. I'm not too
> interested
> > > in the log reduction results, but rather the method used to test AET.
> > > Although it may be unrelated to this recall since a sporeformer is
> > > involved, without disclosing too much the method used matters quite a
> lot.
> > >
> > > Best regards,
> > >
> > > —Robert P.
> > >
> > > -----Original Message-----
> > > From: The Pharmaceutical Microbiology Forum Email List <
> > > [log in to unmask]> On Behalf Of Tony Cundell
> > > (External)
> > > Sent: Thursday, March 16, 2023 18:14
> > > To: [log in to unmask]
> > > Subject: Re: [PMFLIST] Atovaquone Oral Suspension Recall
> > >
> > > Don,
> > >
> > > If the spores germinate (the contamination is most likely to be in the
> > > form of spores) their growth would be prevented by the benzyl alcohol.
> > >
> > > A reduced water activity and low pH will inhibit spore germination.
> > >
> > > I provided the formulation in my original post.
> > >
> > > Each 5 mL of MEPRON oral suspension contains 750 mg of atovaquone and
> the
> > > inactive ingredients benzyl alcohol, flavor, poloxamer 188, purified
> water,
> > > saccharin sodium, and xanthan gum.
> > >
> > > Tony
> > >
> > >
> > >
> > >
> > > On Thu, Mar 16, 2023 at 7:24 PM Donald English <
> > > [log in to unmask]>
> > > wrote:
> > >
> > > > Dear Tony,
> > > >
> > > > Benzyl alcohol is a bacteriostatic preservative and is mostly active
> > > > against Gram-positive bacteria such Gram-positive cocci.  It can
> > > > inhibit the grow of yeast and mold at a concentration between 2500
> and
> > > 5000 ug/ml.
> > > > However, Benzyl alcohol is inactive against spores.  If this Benzyl
> > > > alcohol preserved product is contaminated with a Gram-positive
> bacilli
> > > > that is a spore former, it will not reduce the count of these
> > > > organisms.  To have activity against a spore forming Gram-positive
> > > > bacilli, a cidal preservative that has activity against bacterial and
> > > > mold spores should have been included as part of the preservative
> > > > system in addition to Benzyl alcohol.
> > > >
> > > > Because Benzyl alcohol is present in the formulation, it may be
> > > > possible for a spore forming Gram-positive bacilli to grow in the
> > > > product if there is a sufficient concentration of microbial nutrients
> > > > present in the formulation.  However, I do not have access to the
> > > > inactive ingredients that is present in the product formulation to
> > > > determine whether this is even possible.
> > > >
> > > > I suspect that Bacillus cereus contamination of this product could
> > > > occur either during manufacturing or during consumer usage.  I
> suspect
> > > > that it is more highly likely that this contamination could during
> > > > consumer usage because Bacillus cereus is present everywhere in the
> > > environment.
> > > >
> > > > Don
> > > >
> > > > Donald J. English Microbiological Quality Consulting LLC Florham
> Park,
> > > > New Jersey 07932.
> > > >
> > > > Sent from my iPhone
> > > >
> > > > > On Mar 16, 2023, at 1:58 PM, Tony Cundell <[log in to unmask]>
> > > wrote:
> > > > >
> > > > > Don,
> > > > >
> > > > > I am aware of the indication of this oral suspension.
> > > > >
> > > > > I agree we do not have adequate information as to whether bacterial
> > > > spores
> > > > > would germinate, and grow in the product. It does contain 1% benzyl
> > > > > alcohol which is most effective against Gram-positive bacteria
> > > > >
> > > > > I believe that the clinical literature does not identify low
> levels of
> > > B.
> > > > > subtilis in an oral dosage form as a hazard to immunosuppressed
> > > > > populations. If that was the case, what foods could they consume?
> > > > >
> > > > > Tony
> > > > >
> > > > >> On Thu, Mar 16, 2023 at 11:49 AM Donald English <
> > > > >> [log in to unmask]> wrote:
> > > > >>
> > > > >> Dear all,
> > > > >>
> > > > >> I think that some additional information is required to understand
> > > > >> as to why possible Bacillus cereus contamination of Atovaquone
> Oral
> > > > >> Suspension might be objectionable and why this product is being
> > > > >> recalled.  Atovaquone Oral Suspension, USP is indicated for
> > > > >> prevention and treatment of Pneumocystis jiroveci pneumonia (PCP)
> > > > >> in adults and children who cannot tolerate other medicines, such
> as
> > > > >> trimethoprim-sulfamethoxazole.  For your information, Pneumocystis
> > > > >> jiroveci pneumonia is a type of pneumonia that is most likely to
> > > > >> affect people with human immunodeficiency virus (HIV) and is also
> > > > >> used to prevent immunocompromised patients from contracting this
> > > > >> type of pneumonia.  In immunocompromised individuals, the
> microbial
> > > > >> contamination in this type of product could lead to
> > > > >> life-threatening infections such as endocarditis and necrotizing
> > > > >> soft tissue infections.  In conclusion, this product is never used
> > > > >> by individuals who are not immunocompromised.
> > > > >>
> > > > >> Don
> > > > >>
> > > > >> Donald J. English Microbiological Quality Consulting LLC Florham
> > > > >> Park, New Jersey 07932
> > > > >>
> > > > >>> On Wed, Mar 15, 2023 at 11:56 AM Tony Cundell
> > > > >>> <[log in to unmask]>
> > > > >>> wrote:
> > > > >>>
> > > > >>> I did publish an article on this topic.
> > > > >>>
> > > > >>> Cundell, T. Is *Bacillus subtilis* Objectionable in an Oral
> Liquid
> > > > >> Solution
> > > > >>> Amer. Pharm. Rev. 23 (2): 44-47 2020
> > > > >>>
> > > > >>> On Wed, Mar 15, 2023 at 10:12 AM Reza Garakoui
> > > > >>> <[log in to unmask]
> > > > >
> > > > >>> wrote:
> > > > >>>
> > > > >>>> Yes, I agree with you and also B.licheniformis were seen in raw
> > > > >> material
> > > > >>>> and many personals but there weren’t any data about this
> > > > >>>> microorganism
> > > > >> in
> > > > >>>> USP.
> > > > >>>>
> > > > >>>> On Wed, Mar 15, 2023 at 02:17 Dr. Michael J. Miller <
> > > > >>>> [log in to unmask]>
> > > wrote:
> > > > >>>>
> > > > >>>>> Contamination could have occurred from unit operations and
> other
> > > > >> sources.
> > > > >>>>> As such, B. cereus spores could remain viable in the product.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> The presence of B. cereus in an oral formulation is
> > > > >>>>> objectionable
> > > > >> based
> > > > >>>> on
> > > > >>>>> the potential regulatory risk and uncertain risk to the
> patient.
> > > > >> There
> > > > >>>> are
> > > > >>>>> no good data available on the infectious dose of this organism
> > > > >>>>> in the healthy human, although cases of B. cereus pneumonia are
> > > known.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> FDA is concerned about Bacillus cereus as a food contaminant.
> > > > >>>>> The
> > > > >> FDA Bad
> > > > >>>>> Bug Book states that an estimated 63,400 cases of self-limiting
> > > > >> diarrheal
> > > > >>>>> disease occur annually. This disease is due to the production
> of
> > > > >>>>> enterotoxin, and the FDA states “The number of organisms most
> > > > >>>>> often associated with human illness is 105 to 108; however, the
> > > > >> pathogenicity
> > > > >>>>> arises from preformed toxin.”
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Gaur (2001) notes that pneumonia caused by B. cereus is
> > > > >>>>> possible, but unlikely and restricted to immunocompromised
> > > > >>>>> patients. However,
> > > > >> Bottone
> > > > >>>>> (2011) presents a very different picture, discussing multiple
> > > > >>>>> cases
> > > > >> of
> > > > >>>>> infection occurring through the oral and nasal routes among
> > > > >>>>> healthy individuals.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Gaur, AH and JL Shenep. 2001. The Expanding Spectrum Of
> Diseases
> > > > >> Caused
> > > > >>>> By
> > > > >>>>> Bacillus cereus. Ped Infect Dis J 20(5):533-534.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Bottone, EJ. 2010. Bacillus cereus, a Volatile Human Pathogen.
> > > > >>>>> Clin Microbiol Rev 23(2):382‐398.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> From: The Pharmaceutical Microbiology Forum Email List <
> > > > >>>>> [log in to unmask]> on behalf of Tony
> Cundell
> > > > >>>>> < [log in to unmask]>
> > > > >>>>> Reply-To: The Pharmaceutical Microbiology Forum Email List <
> > > > >>>>> [log in to unmask]>
> > > > >>>>> Date: Tuesday, March 14, 2023 at 5:44 PM
> > > > >>>>> To: <[log in to unmask]>
> > > > >>>>> Subject: [PMFLIST] Atovaquone Oral Suspension Recall
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> This is interesting.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Camber Pharmaceuticals is voluntarily recalling lot #E220182 of
> > > > >>>> Atovaquone
> > > > >>>>>
> > > > >>>>> Oral Suspension, USP 750mg/5mL to the Consumer/User level, due
> > > > >>>>> to the
> > > > >>>>>
> > > > >>>>> potential Bacillus cereus contamination in the product.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> My interest is whether B. cereus spores would survive,
> germinate
> > > > >>>>> or
> > > > >> grow
> > > > >>>> in
> > > > >>>>>
> > > > >>>>> this product that has a reduced water activity, 1% benzyl
> > > > >>>>> alcohol,
> > > > >> and
> > > > >>>>>
> > > > >>>>> possibly a low pH?
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Based on my internet search:
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Atovaquone is a yellow crystalline solid that is practically
> > > > >> insoluble in
> > > > >>>>>
> > > > >>>>> water. MEPRON oral suspension is a formulation of micro-fine
> > > > >> particles of
> > > > >>>>>
> > > > >>>>> atovaquone.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Each 5 mL of MEPRON oral suspension contains 750 mg of
> > > > >>>>> atovaquone
> > > > >> and the
> > > > >>>>>
> > > > >>>>> inactive ingredients benzyl alcohol, flavor, poloxamer 188,
> > > > >>>>> purified
> > > > >>>> water,
> > > > >>>>>
> > > > >>>>> saccharin sodium, and xanthan gum.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> *Qualitative and quantitative composition*
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Each ml of suspension contains 150 mg atovaquone.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> A unit dose of 5 ml contains 750 mg atovaquone.
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> Excipient with known effect: Each 5 ml of oral suspension
> > > > >>>>> contains
> > > > >> 50.00
> > > > >>>> mg
> > > > >>>>>
> > > > >>>>> benzyl alcohol
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> 50 mg/5 mL, i.e., 1000 mg/100 mL or 1% Benzyl Alcohol
> > > > >>>>>
> > > > >>>>> --
> > > > >>>>>
> > > > >>>>> Tony Cundell, Ph. D.
> > > > >>>>>
> > > > >>>>> Consulting Microbiologist
> > > > >>>>>
> > > > >>>>> Email: [log in to unmask]
> > > > >>>>>
> > > > >>>>> Cell: 914 841-0074
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
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> > > > >>>>>
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> > > > >> the
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> sponsors
> > > > >>>>> of
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> -YgRXkhLLX1qFVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5a
> > > > >>>>>
> NXxKvKz1p7Pj3JeXef_1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe
> > > > >>>>>
> 1IKn-S6n3kyVG1RiRYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBV
> > > > >>>>>
> N9CbOYFmAXJqUOg4t_h2bk2NMdyHpUTQDiz6eI5uTJ560V5uiC9kpjezmgRoujhE
> > > > >>>>>
> Xodcg5DX6EMLeRlPnwOjU-b2VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW
> > > > >>>>> 2NyJ7321jC-jQHUCaGF5p3bK7xGM4/http%3A%2F%
> 2Fwww.microbiologics.co
> > > > >>>>> m
> > > > >>>>>
> > > > >>>>> Novatek International
> > > > >>>>>
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86Ealv
> > > > >>>>>
> wbrUN6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAkn
> > > > >>>>>
> umJYaFKC-4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56
> > > > >>>>>
> AE67tBM_S8OA0Oq63aEeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1
> > > > >>>>>
> BMG5PM3YHhCTYEww9atPpOZb1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW
> > > > >>>>>
> 6PMhB5QPf1JafqPJQIJc4DYR60c8D191IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGS
> > > > >>>>>
> TI31Phbh0jg2nCkdiltpbfy8c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZK
> > > > >>>>> hZJg_mGu7NtnQ7BWCioDLVnbR71wZu/https%3A%2F%2Fntint.com%2F
> > > > >>>>>
> > > > >>>>> Steris -
> > > > >>>>>
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ
> > > > >>>>>
> 0RdjPHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwU
> > > > >>>>>
> nnYaWea1ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwke
> > > > >>>>>
> rUy2NlY6rPIgXXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4
> > > > >>>>>
> fk735P8LfYLrQNcgkFX1ssiSl79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx
> > > > >>>>>
> _IAm7H5WAn-IhhC1f_qls6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL1
> > > > >>>>>
> 4Ij7gmkDIqmvK_8lsviuMDh7Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQ
> > > > >>>>>
> Oak3nd-m2w9Z__n1us3WqJZz2IH7S/http%3A%2F%2Fwww.sterislifescience
> > > > >>>>> s.com%2F
> > > > >>>>>
> > > > >>>>> Veltek Associates, Inc -
> > > > >>>>>
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slg
> > > > >>>>>
> z6dJRkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7
> > > > >>>>>
> yKPzrmj7D1_yeKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owm
> > > > >>>>>
> NN9BTdaRixsPp2idsDMSpoKd3UC5ZaKx6EfjebpKPLDLi_iBT3__OctmE3i6ei7d
> > > > >>>>>
> 1tifzS7BbjexWp1a4BkHFZV0zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPW
> > > > >>>>>
> LGVpXtubui-8Zqpl3SqtbUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe
> > > > >>>>>
> 9x4qqaPFXKk36vCJo2Cof-OnWKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL
> > > > >>>>> 7hjsxHv0Xa7YFlaWqwMNj-E9174cL/http%3A%2F%2Fwww.sterile.com
> > > > >>>>>
> > > > >>>>>
> > > > >>>>>
> > > > >>>>> ================================= The nature of this service is
> > > > >>>>> to provide a medium for
> > > > >> communication.  The
> > > > >>>>> specific statements and endorsements of individuals
> > > > >>>>> participating in
> > > > >> the
> > > > >>>>> discussions are not necessarily those of the PMF or the
> sponsors
> > > > >>>>> of
> > > > >> the
> > > > >>>>> list.
> > > > >>>>>
> > > > >>>>
> > > > >>>> ------------------
> > > > >>>> The PMFList is supported by our sponsors as a service to the
> > > > scientific
> > > > >>>> community.
> > > > >>>>
> > > > >>>> Please take a second to visit our sponsors' web sites.  Let them
> > > > >>>> know
> > > > >> you
> > > > >>>> saw them on our list and appreciate their support of this
> service.
> > > > >>>>
> > > > >>>> If your company would be interested in sponsoring this
> community,
> > > > >> please
> > > > >>>> contact [log in to unmask] or by completing the
> > > > sponsorship
> > > > >>>> form here: https://bit.ly/3FsEVrW
> > > > >>>>
> > > > >>>>
> > > > >>>>
> > > > >>>> Current Sponsors:
> > > > >>>>
> > > > >>>> Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > > > >>>>
> > > > >>>> Microbiologics, Inc. -
> > > > >>>>
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS
> > > > >>>>
> 8RV60R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-Y
> > > > >>>>
> gRXkhLLX1qFVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5aNXx
> > > > >>>>
> KvKz1p7Pj3JeXef_1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe1IKn
> > > > >>>>
> -S6n3kyVG1RiRYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbO
> > > > >>>>
> YFmAXJqUOg4t_h2bk2NMdyHpUTQDiz6eI5uTJ560V5uiC9kpjezmgRoujhEXodcg5
> > > > >>>>
> DX6EMLeRlPnwOjU-b2VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ732
> > > > >>>> 1jC-jQHUCaGF5p3bK7xGM4/http%3A%2F%2Fwww.microbiologics.com
> > > > >>>>
> > > > >>>> Novatek International
> > > > >>>>
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86Ealvw
> > > > >>>>
> brUN6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknum
> > > > >>>>
> JYaFKC-4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE6
> > > > >>>>
> 7tBM_S8OA0Oq63aEeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1BMG5
> > > > >>>>
> PM3YHhCTYEww9atPpOZb1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW6PMhB
> > > > >>>>
> 5QPf1JafqPJQIJc4DYR60c8D191IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGSTI31Ph
> > > > >>>>
> bh0jg2nCkdiltpbfy8c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZKhZJg_mG
> > > > >>>> u7NtnQ7BWCioDLVnbR71wZu/https%3A%2F%2Fntint.com%2F
> > > > >>>>
> > > > >>>> Steris -
> > > > >>>>
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0
> > > > >>>>
> RdjPHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnn
> > > > >>>>
> YaWea1ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy
> > > > >>>>
> 2NlY6rPIgXXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk73
> > > > >>>>
> 5P8LfYLrQNcgkFX1ssiSl79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx_IAm7
> > > > >>>>
> H5WAn-IhhC1f_qls6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gm
> > > > >>>>
> kDIqmvK_8lsviuMDh7Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-
> > > > >>>> m2w9Z__n1us3WqJZz2IH7S/http%3A%2F%2Fwww.sterislifesciences.com
> %2F
> > > > >>>>
> > > > >>>> Veltek Associates, Inc -
> > > > >>>>
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz
> > > > >>>>
> 6dJRkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yK
> > > > >>>>
> Pzrmj7D1_yeKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owmNN9
> > > > >>>>
> BTdaRixsPp2idsDMSpoKd3UC5ZaKx6EfjebpKPLDLi_iBT3__OctmE3i6ei7d1tif
> > > > >>>>
> zS7BbjexWp1a4BkHFZV0zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPWLGVpX
> > > > >>>>
> tubui-8Zqpl3SqtbUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqa
> > > > >>>>
> PFXKk36vCJo2Cof-OnWKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv
> > > > >>>> 0Xa7YFlaWqwMNj-E9174cL/http%3A%2F%2Fwww.sterile.com
> > > > >>>>
> > > > >>>>
> > > > >>>>
> > > > >>>> ================================= The nature of this service is
> > > > >>>> to provide a medium for communication.
> > > > >> The
> > > > >>>> specific statements and endorsements of individuals
> participating
> > > > >>>> in
> > > > >> the
> > > > >>>> discussions are not necessarily those of the PMF or the sponsors
> > > > >>>> of
> > > > the
> > > > >>>> list.
> > > > >>>>
> > > > >>>
> > > > >>>
> > > > >>> --
> > > > >>> Tony Cundell, Ph. D.
> > > > >>> Consulting Microbiologist
> > > > >>> Email: [log in to unmask]
> > > > >>> Phone: 914 725-3947
> > > > >>> Cell: 914 841-0074
> > > > >>>
> > > > >>> ------------------
> > > > >>> The PMFList is supported by our sponsors as a service to the
> > > > >>> scientific
> > > > >> community.
> > > > >>>
> > > > >>> Please take a second to visit our sponsors' web sites.  Let them
> > > > >>> know
> > > > >> you saw them on our list and appreciate their support of this
> service.
> > > > >>>
> > > > >>> If your company would be interested in sponsoring this community,
> > > > please
> > > > >> contact [log in to unmask] or by completing the
> > > > >> sponsorship form here: https://bit.ly/3FsEVrW
> > > > >>>
> > > > >>>
> > > > >>>
> > > > >>> Current Sponsors:
> > > > >>>
> > > > >>> Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > > > >>>
> > > > >>> Microbiologics, Inc. -
> > > > >>>
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS8
> > > > >>>
> RV60R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-YgR
> > > > >>>
> XkhLLX1qFVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5aNXxKvK
> > > > >>>
> z1p7Pj3JeXef_1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe1IKn-S6n
> > > > >>>
> 3kyVG1RiRYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbOYFmAX
> > > > >>>
> JqUOg4t_h2bk2NMdyHpUTQDiz6eI5uTJ560V5uiC9kpjezmgRoujhEXodcg5DX6EML
> > > > >>>
> eRlPnwOjU-b2VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ7321jC-jQH
> > > > >>> UCaGF5p3bK7xGM4/http%3A%2F%2Fwww.microbiologics.com
> > > > >>>
> > > > >>> Novatek International
> > > > >>>
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86Ealvwb
> > > > >>>
> rUN6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknumJY
> > > > >>>
> aFKC-4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE67tB
> > > > >>>
> M_S8OA0Oq63aEeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1BMG5PM3Y
> > > > >>>
> HhCTYEww9atPpOZb1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW6PMhB5QPf1
> > > > >>>
> JafqPJQIJc4DYR60c8D191IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGSTI31Phbh0jg2
> > > > >>>
> nCkdiltpbfy8c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZKhZJg_mGu7NtnQ7
> > > > >>> BWCioDLVnbR71wZu/https%3A%2F%2Fntint.com%2F
> > > > >>>
> > > > >>> Steris -
> > > > >>>
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0R
> > > > >>>
> djPHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnnYa
> > > > >>>
> Wea1ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy2Nl
> > > > >>>
> Y6rPIgXXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk735P8L
> > > > >>>
> fYLrQNcgkFX1ssiSl79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx_IAm7H5WAn
> > > > >>>
> -IhhC1f_qls6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gmkDIqmv
> > > > >>>
> K_8lsviuMDh7Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-m2w9Z__
> > > > >>> n1us3WqJZz2IH7S/http%3A%2F%2Fwww.sterislifesciences.com%2F
> > > > >>>
> > > > >>> Veltek Associates, Inc -
> > > > >>>
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz6
> > > > >>>
> dJRkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yKPz
> > > > >>>
> rmj7D1_yeKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owmNN9BTd
> > > > >>>
> aRixsPp2idsDMSpoKd3UC5ZaKx6EfjebpKPLDLi_iBT3__OctmE3i6ei7d1tifzS7B
> > > > >>>
> bjexWp1a4BkHFZV0zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPWLGVpXtubui
> > > > >>>
> -8Zqpl3SqtbUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqaPFXKk3
> > > > >>>
> 6vCJo2Cof-OnWKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv0Xa7YFl
> > > > >>> aWqwMNj-E9174cL/http%3A%2F%2Fwww.sterile.com
> > > > >>>
> > > > >>>
> > > > >>>
> > > > >>> =================================
> > > > >>> The nature of this service is to provide a medium for
> communication.
> > > > >> The specific statements and endorsements of individuals
> > > > >> participating in the discussions are not necessarily those of the
> > > > >> PMF or the sponsors of
> > > > the
> > > > >> list.
> > > > >>
> > > > >> ------------------
> > > > >> The PMFList is supported by our sponsors as a service to the
> > > > >> scientific community.
> > > > >>
> > > > >> Please take a second to visit our sponsors' web sites.  Let them
> > > > >> know
> > > > you
> > > > >> saw them on our list and appreciate their support of this service.
> > > > >>
> > > > >> If your company would be interested in sponsoring this community,
> > > > >> please contact [log in to unmask] or by completing the
> > > > >> sponsorship form here: https://bit.ly/3FsEVrW
> > > > >>
> > > > >>
> > > > >>
> > > > >> Current Sponsors:
> > > > >>
> > > > >> Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > > > >>
> > > > >> Microbiologics, Inc. -
> > > > >>
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS8R
> > > > >>
> V60R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-YgRXk
> > > > >>
> hLLX1qFVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5aNXxKvKz1p
> > > > >>
> 7Pj3JeXef_1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe1IKn-S6n3kyV
> > > > >>
> G1RiRYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbOYFmAXJqUOg
> > > > >>
> 4t_h2bk2NMdyHpUTQDiz6eI5uTJ560V5uiC9kpjezmgRoujhEXodcg5DX6EMLeRlPnw
> > > > >>
> OjU-b2VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ7321jC-jQHUCaGF5p
> > > > >> 3bK7xGM4/http%3A%2F%2Fwww.microbiologics.com
> > > > >>
> > > > >> Novatek International
> > > > >>
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86Ealvwbr
> > > > >>
> UN6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknumJYaF
> > > > >>
> KC-4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE67tBM_S
> > > > >>
> 8OA0Oq63aEeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1BMG5PM3YHhCT
> > > > >>
> YEww9atPpOZb1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW6PMhB5QPf1JafqP
> > > > >>
> JQIJc4DYR60c8D191IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGSTI31Phbh0jg2nCkdil
> > > > >>
> tpbfy8c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZKhZJg_mGu7NtnQ7BWCioDL
> > > > >> VnbR71wZu/https%3A%2F%2Fntint.com%2F
> > > > >>
> > > > >> Steris -
> > > > >>
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0Rd
> > > > >>
> jPHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnnYaWe
> > > > >>
> a1ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy2NlY6r
> > > > >>
> PIgXXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk735P8LfYLr
> > > > >>
> QNcgkFX1ssiSl79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx_IAm7H5WAn-IhhC
> > > > >>
> 1f_qls6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gmkDIqmvK_8lsv
> > > > >>
> iuMDh7Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-m2w9Z__n1us3Wq
> > > > >> JZz2IH7S/http%3A%2F%2Fwww.sterislifesciences.com%2F
> > > > >>
> > > > >> Veltek Associates, Inc -
> > > > >>
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz6d
> > > > >>
> JRkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yKPzrm
> > > > >>
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> > > > >>
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> > > > >>
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> > > > >>
> l3SqtbUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqaPFXKk36vCJo2
> > > > >>
> Cof-OnWKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv0Xa7YFlaWqwMNj
> > > > >> -E9174cL/http%3A%2F%2Fwww.sterile.com
> > > > >>
> > > > >>
> > > > >>
> > > > >> =================================
> > > > >> The nature of this service is to provide a medium for
> communication.
> > > > The
> > > > >> specific statements and endorsements of individuals participating
> > > > >> in the discussions are not necessarily those of the PMF or the
> > > > >> sponsors of the list.
> > > > >>
> > > > >
> > > > >
> > > > > --
> > > > > Tony Cundell, Ph. D.
> > > > > Consulting Microbiologist
> > > > > Email: [log in to unmask]
> > > > > Phone: 914 725-3947
> > > > > Cell: 914 841-0074
> > > > >
> > > > > ------------------
> > > > > The PMFList is supported by our sponsors as a service to the
> > > > > scientific
> > > > community.
> > > > >
> > > > > Please take a second to visit our sponsors' web sites.  Let them
> > > > > know
> > > > you saw them on our list and appreciate their support of this
> service.
> > > > >
> > > > > If your company would be interested in sponsoring this community,
> > > > > please
> > > > contact [log in to unmask] or by completing the
> sponsorship
> > > > form here: https://bit.ly/3FsEVrW
> > > > >
> > > > >
> > > > >
> > > > > Current Sponsors:
> > > > >
> > > > > Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > > > >
> > > > > Microbiologics, Inc. -
> > > > >
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS8RV
> > > > >
> 60R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-YgRXkhL
> > > > >
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> > > > >
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> > > > >
> RYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbOYFmAXJqUOg4t_h2
> > > > >
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> > > > >
> VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ7321jC-jQHUCaGF5p3bK7xGM
> > > > > 4/http%3A%2F%2Fwww.microbiologics.com
> > > > >
> > > > > Novatek International
> > > > >
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86EalvwbrU
> > > > >
> N6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknumJYaFKC
> > > > >
> -4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE67tBM_S8OA
> > > > >
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> > > > >
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> > > > >
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> > > > >
> c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZKhZJg_mGu7NtnQ7BWCioDLVnbR71w
> > > > > Zu/https%3A%2F%2Fntint.com%2F
> > > > >
> > > > > Steris -
> > > > >
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0Rdj
> > > > >
> PHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnnYaWea1
> > > > >
> ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy2NlY6rPIg
> > > > >
> XXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk735P8LfYLrQNcg
> > > > >
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> > > > >
> s6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gmkDIqmvK_8lsviuMDh7
> > > > >
> Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-m2w9Z__n1us3WqJZz2IH7
> > > > > S/http%3A%2F%2Fwww.sterislifesciences.com%2F
> > > > >
> > > > > Veltek Associates, Inc -
> > > > >
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz6dJ
> > > > >
> RkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yKPzrmj7
> > > > >
> D1_yeKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owmNN9BTdaRixsP
> > > > >
> p2idsDMSpoKd3UC5ZaKx6EfjebpKPLDLi_iBT3__OctmE3i6ei7d1tifzS7BbjexWp1a
> > > > >
> 4BkHFZV0zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPWLGVpXtubui-8Zqpl3Sqt
> > > > >
> bUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqaPFXKk36vCJo2Cof-On
> > > > >
> WKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv0Xa7YFlaWqwMNj-E9174c
> > > > > L/http%3A%2F%2Fwww.sterile.com
> > > > >
> > > > >
> > > > >
> > > > > =================================
> > > > > The nature of this service is to provide a medium for
> communication.
> > > > The specific statements and endorsements of individuals participating
> > > > in the discussions are not necessarily those of the PMF or the
> > > > sponsors of the list.
> > > >
> > > > ------------------
> > > > The PMFList is supported by our sponsors as a service to the
> > > > scientific community.
> > > >
> > > > Please take a second to visit our sponsors' web sites.  Let them know
> > > > you saw them on our list and appreciate their support of this
> service.
> > > >
> > > > If your company would be interested in sponsoring this community,
> > > > please contact [log in to unmask] or by completing the
> > > > sponsorship form here: https://bit.ly/3FsEVrW
> > > >
> > > >
> > > >
> > > > Current Sponsors:
> > > >
> > > > Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > > >
> > > > Microbiologics, Inc. -
> > > >
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS8RV60
> > > >
> R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-YgRXkhLLX1q
> > > >
> FVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5aNXxKvKz1p7Pj3JeXef
> > > >
> _1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe1IKn-S6n3kyVG1RiRYI_Rxox
> > > >
> xsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbOYFmAXJqUOg4t_h2bk2NMdyHpU
> > > >
> TQDiz6eI5uTJ560V5uiC9kpjezmgRoujhEXodcg5DX6EMLeRlPnwOjU-b2VYEwkffEc-C3
> > > >
> XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ7321jC-jQHUCaGF5p3bK7xGM4/http%3A%2F%2
> > > > Fwww.microbiologics.com
> > > >
> > > > Novatek International
> > > >
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86EalvwbrUN6
> > > >
> jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknumJYaFKC-4D2
> > > >
> lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE67tBM_S8OA0Oq63a
> > > >
> EeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1BMG5PM3YHhCTYEww9atPpOZb
> > > >
> 1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW6PMhB5QPf1JafqPJQIJc4DYR60c8D1
> > > >
> 91IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGSTI31Phbh0jg2nCkdiltpbfy8c8pLDIEWFueS
> > > >
> yxayxzlTU7flf1LGkcyVadxPREZKhZJg_mGu7NtnQ7BWCioDLVnbR71wZu/https%3A%2F
> > > > %2Fntint.com%2F
> > > >
> > > > Steris -
> > > >
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0RdjPH
> > > >
> k3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnnYaWea1ioFI
> > > >
> -8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy2NlY6rPIgXXRKBE
> > > >
> kOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk735P8LfYLrQNcgkFX1ssiS
> > > >
> l79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx_IAm7H5WAn-IhhC1f_qls6uMb_aySv
> > > >
> ra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gmkDIqmvK_8lsviuMDh7Vez_YSAWR9Yx
> > > >
> 0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-m2w9Z__n1us3WqJZz2IH7S/http%3A%2F%2
> > > > Fwww.sterislifesciences.com%2F
> > > >
> > > > Veltek Associates, Inc -
> > > >
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz6dJRk
> > > >
> Y8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yKPzrmj7D1_y
> > > >
> eKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owmNN9BTdaRixsPp2idsD
> > > >
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> > > >
> zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPWLGVpXtubui-8Zqpl3SqtbUJHvMziSG
> > > >
> tkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqaPFXKk36vCJo2Cof-OnWKsYhkRhvel7
> > > >
> 9pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv0Xa7YFlaWqwMNj-E9174cL/http%3A%2F%2
> > > > Fwww.sterile.com
> > > >
> > > >
> > > >
> > > > =================================
> > > > The nature of this service is to provide a medium for communication.
> > > > The specific statements and endorsements of individuals participating
> > > > in the discussions are not necessarily those of the PMF or the
> > > > sponsors of the list.
> > > >
> > >
> > >
> > > --
> > > Tony Cundell, Ph. D.
> > > Consulting Microbiologist
> > > Email: [log in to unmask]
> > > Phone: 914 725-3947
> > > Cell: 914 841-0074
> > >
> > > ------------------
> > > The PMFList is supported by our sponsors as a service to the scientific
> > > community.
> > >
> > > Please take a second to visit our sponsors' web sites.  Let them know
> you
> > > saw them on our list and appreciate their support of this service.
> > >
> > > If your company would be interested in sponsoring this community,
> please
> > > contact [log in to unmask] or by completing the sponsorship
> > > form here: https://bit.ly/3FsEVrW
> > >
> > >
> > >
> > > Current Sponsors:
> > >
> > > Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > >
> > > Microbiologics, Inc. -
> > >
> http://secure-web.cisco.com/11JfXAk1iVkQj5WIr25mm5f-szZ536n_ix_lS8RV60R2XuONU_Ainjvzhx0ehQ-oSxx6HDe6KlwUhZJjdODrnOeBYDHGU-sQ_qYx-YgRXkhLLX1qFVddKJToa204nI_ovPc03bsffO-mSUNTFEGDnI1yQNBRdBUpSH5aNXxKvKz1p7Pj3JeXef_1JSDlGMgRU67wgLAwgeXeij_6tknXMwSE4yC3L8PY32Xe1IKn-S6n3kyVG1RiRYI_RxoxxsEobD4vQoUs0dK3BtdGOVAdgsG1JTwjFpW0XKBVN9CbOYFmAXJqUOg4t_h2bk2NMdyHpUTQDiz6eI5uTJ560V5uiC9kpjezmgRoujhEXodcg5DX6EMLeRlPnwOjU-b2VYEwkffEc-C3XmkHQYE57aoR2U7Mcl1S8lGDsDuW2NyJ7321jC-jQHUCaGF5p3bK7xGM4/http%3A%2F%2Fwww.microbiologics.com
> > >
> > > Novatek International
> > >
> https://secure-web.cisco.com/1GBP74SwN6uuVqDLfL4ZDiKrJlxFf86EalvwbrUN6jYC84gnVMPoMCLfzeM2HMHrd3IVVBWaF_BSJ2agb8rRcmrSeKCe4VenAknumJYaFKC-4D2lQNT7lZupj0Kt60DaalZJST6M74yVXw3Ldt0r38HueZyASCPgA56AE67tBM_S8OA0Oq63aEeXELqPT2PIJSWi7eLhu7ovtukxL5u5u8coE-jHk2G8xQ1BMG5PM3YHhCTYEww9atPpOZb1EuUKC6YKvK6VSliHvBQSLAUr3y-rARkwhnn6pMW6PMhB5QPf1JafqPJQIJc4DYR60c8D191IF1DYFqN8kuIxoU7kWPcnypEmEIH6BGSTI31Phbh0jg2nCkdiltpbfy8c8pLDIEWFueSyxayxzlTU7flf1LGkcyVadxPREZKhZJg_mGu7NtnQ7BWCioDLVnbR71wZu/https%3A%2F%2Fntint.com%2F
> > >
> > > Steris -
> > >
> http://secure-web.cisco.com/1GwsdJeE2ZB7i6oszdYb7IjrcG-xXk5wIxGZ0RdjPHk3gnCTriCH7PuGubk83FGIEm0GBjzgmT-STlzS0ymUkF2blelcXyaCJrwUnnYaWea1ioFI-8WjqvTeB4lsfs4CGb2kVvGWJQ6Zlz9FNXQ7GrZ1x-plNaQqvwkerUy2NlY6rPIgXXRKBEkOys7Zls5-iMo2Sp0F4Smn40U3Hc6tJs9oQY4Sd69XXpq4fk735P8LfYLrQNcgkFX1ssiSl79TtOF6zllqPR_IRo3HMMWzbcMgcGKXCyr1jwIx_IAm7H5WAn-IhhC1f_qls6uMb_aySvra5uJzOL499g3jqL0wk1DQxrx3kNpQ1pL14Ij7gmkDIqmvK_8lsviuMDh7Vez_YSAWR9Yx0hcxXkTA2yMGKZ7LvheS0NLoNlYQOak3nd-m2w9Z__n1us3WqJZz2IH7S/http%3A%2F%2Fwww.sterislifesciences.com%2F
> > >
> > > Veltek Associates, Inc -
> > >
> http://secure-web.cisco.com/1KbYk2K26ADO7gSqp04WfhHVCUq57B8m6slgz6dJRkY8U38QDdMi_99oc_b1iRc_nmsjjAZAkiSZ9VXqz6dm4HMbwLyX19Jy1eL7yKPzrmj7D1_yeKRqHtb36fpuEJWkKBYgIfnnpd3659jEz3GNpV68VYjnSYJr3owmNN9BTdaRixsPp2idsDMSpoKd3UC5ZaKx6EfjebpKPLDLi_iBT3__OctmE3i6ei7d1tifzS7BbjexWp1a4BkHFZV0zrAlbjjj-qWR6JH_w4FtUmJh4eM3niNgzDholLPWLGVpXtubui-8Zqpl3SqtbUJHvMziSGtkpy0S8o4L4gYZKE5okN5wOEjC_wJ3tTBe9x4qqaPFXKk36vCJo2Cof-OnWKsYhkRhvel79pV_RLveju4gpRPtPXNV_SsJ7UXL7hjsxHv0Xa7YFlaWqwMNj-E9174cL/http%3A%2F%2Fwww.sterile.com
> > >
> > >
> > >
> > > =================================
> > > The nature of this service is to provide a medium for communication.
> The
> > > specific statements and endorsements of individuals participating in
> the
> > > discussions are not necessarily those of the PMF or the sponsors of the
> > > list.
> > >
> > >
> > > This message is intended solely for the designated recipient(s). It may
> > > contain confidential or proprietary information and may be subject to
> > > attorney-client privilege or other confidentiality protections. If you
> are
> > > not a designated recipient you may not review, copy or distribute this
> > > message. If you receive this in error, please notify the sender by
> reply
> > > e-mail and delete this message. Thank you.
> > >
> > > ------------------
> > > The PMFList is supported by our sponsors as a service to the scientific
> > > community.
> > >
> > > Please take a second to visit our sponsors' web sites.  Let them know
> you
> > > saw them on our list and appreciate their support of this service.
> > >
> > > If your company would be interested in sponsoring this community,
> please
> > > contact [log in to unmask] or by completing the sponsorship
> > > form here: https://bit.ly/3FsEVrW
> > >
> > >
> > >
> > > Current Sponsors:
> > >
> > > Associates of Cape Cod, Inc. - http://www.acciusa.com/
> > >
> > > Microbiologics, Inc. - http://www.microbiologics.com
> > >
> > > Novatek International https://ntint.com/
> > >
> > > Steris - http://www.sterislifesciences.com/
> > >
> > > Veltek Associates, Inc - http://www.sterile.com
> > >
> > >
> > >
> > > =================================
> > > The nature of this service is to provide a medium for communication.
> The
> > > specific statements and endorsements of individuals participating in
> the
> > > discussions are not necessarily those of the PMF or the sponsors of the
> > > list.
> > >
> >
> >
> > --
> > Tony Cundell, Ph. D.
> > Consulting Microbiologist
> > Email: [log in to unmask]
> > Phone: 914 725-3947
> > Cell: 914 841-0074
> >
> > ------------------
> > The PMFList is supported by our sponsors as a service to the scientific
> community.
> >
> > Please take a second to visit our sponsors' web sites.  Let them know
> you saw them on our list and appreciate their support of this service.
> >
> > If your company would be interested in sponsoring this community, please
> contact [log in to unmask] or by completing the sponsorship
> form here: https://bit.ly/3FsEVrW
> >
> >
> >
> > Current Sponsors:
> >
> > Associates of Cape Cod, Inc. - http://www.acciusa.com/
> >
> > Microbiologics, Inc. - http://www.microbiologics.com
> >
> > Novatek International https://ntint.com/
> >
> > Steris - http://www.sterislifesciences.com/
> >
> > Veltek Associates, Inc - http://www.sterile.com
> >
> >
> >
> > =================================
> > The nature of this service is to provide a medium for communication.
> The specific statements and endorsements of individuals participating in
> the discussions are not necessarily those of the PMF or the sponsors of the
> list.
>
> ------------------
> The PMFList is supported by our sponsors as a service to the scientific
> community.
>
> Please take a second to visit our sponsors' web sites.  Let them know you
> saw them on our list and appreciate their support of this service.
>
> If your company would be interested in sponsoring this community, please
> contact [log in to unmask] or by completing the sponsorship
> form here: https://bit.ly/3FsEVrW
>
>
>
> Current Sponsors:
>
> Associates of Cape Cod, Inc. - http://www.acciusa.com/
>
> Microbiologics, Inc. - http://www.microbiologics.com
>
> Novatek International https://ntint.com/
>
> Steris - http://www.sterislifesciences.com/
>
> Veltek Associates, Inc - http://www.sterile.com
>
>
>
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> The nature of this service is to provide a medium for communication.  The
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-- 
Tony Cundell, Ph. D.
Consulting Microbiologist
Email: [log in to unmask]
Phone: 914 725-3947
Cell: 914 841-0074

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