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May 2001

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Subject:
From:
"Hill, Katherine E." <[log in to unmask]>
Reply To:
The Pharmaceutical Microbiology Mail List <[log in to unmask]>
Date:
Thu, 3 May 2001 10:15:54 -0500
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Hello All-

        I was wondering what the industry practice is for performing
negative controls (time of use sterility check for media) for microbial
limits and preservative effectiveness testing (and any other kinds of
testing)?  Would performing negative controls, after doing the growth
promotion and sterility testing of the media, bring into question your
initial results for the media sterility check?  I've heard that in the
clinical area, conducting negative controls is common, but I would like to
know what other labs outside the clinical area are doing.  Any comments you
have would be greatly appreciated.

Thanks very much,
Cathy Hill
Part Three Microbiologist


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