Hospital purchasing agents often buy the cheapest items for patient use
because of budget constraints.
Ironically they confiscate incoming patient's consumer toiletries and
replace them with substandard, inadequately .
preserved products.
A classic example is using contaminated alcohol free mouthwash in the ICU
for patients on respirators who get lower respiratory tract infections
On Thu, Apr 27, 2023 at 9:00 AM Donald English <[log in to unmask]>
wrote:
> Hi Rick,
>
> In the last 6 months, there were 2 product recalls of shaving cream in
> the UK in which Burkholderia was found to be present. In November
> 2022, a shaving kit called Eco White Carton Shaving Kit had been
> recalled due to the presence of Burkholderia contamination. In
> January 2023, there was a second recall in the UK of a shaving cream
> called Shaving Kit in White Box. Based upon the description that is
> present in this second recall, it matches the information in the Irish
> newspaper article for causing infections. For your information, both
> of these products had been manufactured in China. Based upon pictures
> of these 2 products on the internet, I cannot see the ingredient
> composition to see what preservatives are present in each of these
> products.
>
> Furthermore, both of these 2 recalled shaving creams had been packaged
> in 10-gram tubes. It is not unusual to have the presence of
> Burkholderia contamination in shaving creams because there was a
> United States recall in 1996 due to the presence of Burkholderia
> contamination.
>
> Don
>
> Donald J. English Microbiological Quality Consulting LLC
> Florham Park, New Jersey 07932
>
>
>
> On Wed, Apr 26, 2023 at 1:30 PM Rick Jakober <[log in to unmask]>
> wrote:
> >
> > Thanks Derek!
> >
> > I’m not surprised but I’d like to see more info about the product. I am
> also expecting significant microbial problems in other consumer related
> products especially those that are having their preservative concentrations
> reduced or even eliminated because they are “toxic”. Some grad student
> needs to perform microbial surveys of those refilled hotel shampoos,
> conditioners and body washes. What a perfect opportunity for colonization
> of consumer products by bad actors….humid and warm conditions and a system
> where microorganisms are becoming adapted to the products.
> >
> > Should keep us microbiologists in business for a long time.
> >
> > Rick Jakober
> > VP Lab Services
> > Perritt Laboratories, Inc.
> >
> > > On Apr 26, 2023, at 8:40 AM, D Free <[log in to unmask]> wrote:
> > >
> > > Providing Link to Newspaper Article on the apparent colonisation of
> ICU patients from the use of contaminated shaving cream.
> > >
> > >
> https://www.independent.ie/irish-news/how-shaving-cream-contaminated-with-an-unusual-bug-affected-icu-patients-in-limerick/42447156.htmlhttps://www.independent.ie/irish-news/how-shaving-cream-contaminated-with-an-unusual-bug-affected-icu-patients-in-limerick/42447156.html
> > >
> > > Regards,
> > >
> > > Drerek
> > >
> > >
> > > Dr. Derek Freeman
> > > Principal DFMicro
> > > Microbiology & QA Consultants
> > >
> > > ________________________________
> > > From: The Pharmaceutical Microbiology Forum Email List <
> [log in to unmask]> on behalf of Tony Cundell <
> [log in to unmask]>
> > > Sent: 25 April 2023 23:21
> > > To: [log in to unmask] <
> [log in to unmask]>
> > > Subject: Re: [PMFLIST] Cetrimide growth promotion / Pseudomonas
> aeruginosa low counts
> > >
> > > Deborah,
> > >
> > > One of the issues with growth promotion testing of compendial media
> like
> > > Cetrimide Agar is the medium was not developed for microbial
> enumeration
> > > but as a diagnostic medium for Pseudomonas aeruginosa. For example, the
> > > Difco/BBL Manual indicates there should be good recovery with an
> inoculum
> > > of 10^3 CFU.
> > >
> > > The current USP <62> chapter states:
> > > Test for Growth-Promoting Properties, Solid Media
> > > Perform *Surface-Spread Method *(see *Plate-Count Methods *under
> > > Microbiological
> > > Examination of Nonsterile Products: Microbial Enumeration Tests 〈61〉
> > > <
> https://online.uspnf.com/uspnf/current-document/1_GUID-0392F79D-1F8A-4B8D-BEC8-C6FD7B39966F_1_en-US
> <
> https://online.uspnf.com/uspnf/current-document/1_GUID-0392F79D-1F8A-4B8D-BEC8-C6FD7B39966F_1_en-US
> >>),
> > > inoculating each plate with a small number (not more than 100 cfu) of
> the
> > > appropriate microorganism. Incubate at the specified temperature for
> not
> > > more than the shortest period of time specified in the test. Growth of
> the
> > > microorganism comparable to that previously obtained with a previously
> > > tested and approved batch of medium occurs.
> > >
> > > Although I was a long-term member of the USP Microbiology Expert
> Committee
> > > I never truly supported this approach which was derived from the
> earlier
> > > Ph. Eur chapter. As the test involves a general enrichment step this
> GPT is
> > > a stringent requirement.
> > >
> > > You will need to decide if the consistent lower recovery with the
> inhouse
> > > medium gives lot-to-lot comparability and meets your requirements.
> > >
> > > Tony
> > >
> > >> On Tue, Apr 25, 2023 at 4:54 PM Deborah Edwards <
> > >> [log in to unmask]> wrote:
> > >>
> > >> Hello,
> > >>
> > >> We make our cetrimide plates in-house and add glycerol, as the
> > >> instructions state. Our growth promotion counts are really low
> (typically
> > >> <10) while on TSA or other media, they range in the 20s and 30s.
> > >>
> > >> Does anyone else have this issue and if so, any suggestions as to why
> this
> > >> is happening and/or what to do about it, if anything? I assume the
> other
> > >> media, being non-selective, provides more nutrition for the
> Pseudomonas.
> > >> I know that "<100 CFU" is the USP requirement for GP, but if a count
> is 1/1
> > >> on duplicate plates, is this acceptable?
> > >>
> > >> Thank you,
> > >> Deborah
> > >>
> > >> Regards,
> > >> Deborah Edwards
> > >> Senior Scientist
> > >> Microbiology
> > >>
> > >> Haleon
> > >> Haleon.com
> > >> [log in to unmask]<mailto:[log in to unmask]>
> > >> 804-257-2314
> > >>
> > >> The Earth is a fine place and worth fighting for. - Ernest Hemingway
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> > >
> > > --
> > > Tony Cundell, Ph. D.
> > > Consulting Microbiologist
> > > Email: [log in to unmask]
> > > Phone: 914 725-3947
> > > Cell: 914 841-0074
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>
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>
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>
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>
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> =================================
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--
Tony Cundell, Ph. D.
Consulting Microbiologist
Email: [log in to unmask]
Phone: 914 725-3947
Cell: 914 841-0074
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The PMFList is supported by our sponsors as a service to the scientific community.
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If your company would be interested in sponsoring this community, please contact [log in to unmask] or by completing the sponsorship form here: https://bit.ly/3FsEVrW
Current Sponsors:
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Steris - http://www.sterislifesciences.com/
Veltek Associates, Inc - http://www.sterile.com
Special Process Services, LC - https://www.linkedin.com/in/joseph-connaghan-b663929
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