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October 2009

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From:
"Geis, Phil" <[log in to unmask]>
Reply To:
The Pharmaceutical Microbiology Forum Email List <[log in to unmask]>
Date:
Wed, 14 Oct 2009 22:34:47 -0400
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Cindy - here's an article that also describes

Int J Cosmet Sci. 2009 Jun;31(3):163-75. Epub 2009 Mar 19. Links
Self-preserving cosmetics.Varvaresou A, Papageorgiou S, Tsirivas E,
Protopapa E, Kintziou H, Kefala V, Demetzos C.
Department of Aesthetics and Cosmetology, School of Health & Caring
Professions, Technological Educational Institution, Egaleo, Greece.
[log in to unmask]

Preservatives are added to products for two reasons: first, to prevent
microbial spoilage and therefore to prolong the shelf life of the
product; second, to protect the consumer from a potential infection.
Although chemical preservatives prevent microbial growth, their safety
is questioned by a growing segment of consumers. Therefore, there is a
considerable interest in the development of preservative-free or
self-preserving cosmetics. In these formulations traditional/chemical
preservatives have been replaced by other cosmetic ingredients with
antimicrobial properties that are not legislated as preservatives
according to the Annex VI of the Commission Directive 76/768/EEC and the
amending directives (2003/15/EC, 2007/17/EC and 2007/22/EC). 'Hurdle
Technology', a technology that has been used for the control of product
safety in the food industry since 1970s, has also been applied for the
production of self-preserving cosmetics. 'Hurdle Technology' is a term
used to describe the intelligent combination of different preservation
factors or hurdles to deteriorate the growth of microorganisms.
Adherence to current good manufacturing practice, appropriate packaging,
careful choice of the form of the emulsion, low water activity and low
or high pH values are significant variables for the control of microbial
growth in cosmetic formulations. This paper describes the application of
the basic principles of 'Hurdle Technology' in the production of
self-preserving cosmetics. Multifunctional antimicrobial ingredients and
plant-derived essential oils and extracts that are used as alternative
or natural preservatives and are not listed in Annex VI of the Cosmetic
Directive are also reported.

-----Original Message-----
From: The Pharmaceutical Microbiology Forum Email List
[mailto:[log in to unmask]] On Behalf Of Cindy Jones
Sent: Wednesday, October 14, 2009 5:52 PM
To: [log in to unmask]
Subject: [PMFLIST] hurdle technology

I am looking at some cosmetic preservatives and see gluconolactone and
sodium benzoate (Geogard): the mode of action is said to be 'hurdle
technology' where a more hostile environment is created. Can someone
explain this mode of action further or point me to a site?


 
Cindy Jones, Ph.D., formulator, biochemist
Sagescript Institute, llc


      

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The PMFList (http://microbiol.org/PMFList_info.htm) is operated from
The Microbiology Network (http://microbiol.org) and supported by
our sponsors (http://microbiol.org/sponsor.htm) as a service to
the scientific community.

Please take a second to visit our sponsors' web sites and say thank you for their support of this service.

Accugenix - http://www.accugenix.com

American Type Culture Collection - http://www.atcc.org

Applied Biosystems, MicroSeq Microbial ID System - http://www.microseq.com/

BD Diagnostic Systems - http://www.bd.com/ds/

Biolog - http://www.biolog.com

Biomerieux - http://industry.biomerieux-usa.com

EMD Chemicals - http://www.emdchemicals.com

MicroBioLogics, Inc. - http://www.microbiologics.com

Millipore - http://www.millipore.com

MODA Technology Partners - http://www.modatp.com

Pall - http://www.pall.com

NovaTek International - http://www.ntint.com

Rapid Micro Biosystems - http://www.rapidmicrobio.com  (formerly GPS)

Raven Biological Labs - http://www.ravenlabs.com

Veltek Associates, Inc - http://www.sterile.com

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The nature of this service is to provide a medium for communication.  The specific statements and endorsements of individuals participating in the discussions are not necessarily those of The Microbiology Network, Inc., the PMF, or the sponsors of the list.

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