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April 2017

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Subject:
From:
Van Reindeer Blitzen <[log in to unmask]>
Reply To:
The Pharmaceutical Microbiology Forum Email List <[log in to unmask]>
Date:
Thu, 20 Apr 2017 21:01:44 +0000
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Thanks for your response.


Would it be safe to say that mature leukocytes of either major lineage still require some amount of amino, lipid or carbohydrate intake throughout their life span?

________________________________
发件人: The Pharmaceutical Microbiology Forum Email List <[log in to unmask]> 代表 Barry Bochner <[log in to unmask]>
发送时间: 2017年4月5日 17:38
收件人: [log in to unmask]
主题: Re: [PMFLIST] Leukocytic Metabolism

It is clear from our publication (B. Bochner et al, PLoS One, 2011) that the carbon metabolism can be very different in different types of cells, including stem cells vs differentiated cells and normal cells vs cancer cells.   I have not seen specific analyses of the cell types that you mention in your question.



-----Original Message-----
From: The Pharmaceutical Microbiology Forum Email List [mailto:[log in to unmask]] On Behalf Of Van Reindeer Blitzen
Sent: Wednesday, April 05, 2017 11:34 AM
To: [log in to unmask]
Subject: [PMFLIST] Leukocytic Metabolism

Do such mature leukocytes as basophils, mast cells, eosinophils, macrophages, neutrophils, dendritic cells, Plasma Cells, B cells and T cells have nutritional requirements as other somatocytes, i.e. do they still consume such basic nutrients as carbohydrates, aminos, lipids, vitamins and minerals from their surroundings while circulating in the blood stream or after maturing in tissue, or do they simply retain any nutrients from development during their life span?

In the former case, how do their individual consumption needs change through development phases, i.e. are there any differences in what they consume as a stem cell, pluripotent progenitor, mature leukocyte in circulation and lastly after activation?

Thanks.

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The Microbiology Network (http://microbiologynetwork.com) and supported by
our sponsors as a service to the scientific community.

Please take a second to visit our sponsors' web sites and say thank you for their support of this service.


Veltek Associates, Inc - http://www.sterile.com

Microbiologics, Inc. - http://www.microbiologics.com

Nelson Labs - http://www.nelsonlabs.com

BD Diagnostic Systems - http://www.bd.com/ds/

Boston Analytical http://www.bostonanalytical.com/

MilliporeSigma  http://www.emdmillipore.com/

Charles River Microbial Solutions:  Endosafe, Accugenix & Celsis   - www.criver.com/micro<http://www.criver.com/micro>

Avista Pharma Solutions  http://www.avistapharma.com

Associates of Cape Cod, Inc. - http://www.acciusa.com/


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The nature of this service is to provide a medium for communication.  The specific statements and endorsements of individuals participating in the discussions are not necessarily those of The Microbiology Network, Inc., the PMF, or the sponsors of the list.

------------------
The PMFList (http://microbiologynetwork.com/pmflist.asp) is operated from
The Microbiology Network (http://microbiologynetwork.com) and supported by
our sponsors as a service to the scientific community.

Please take a second to visit our sponsors' web sites and say thank you for their support of this service.


Veltek Associates, Inc - http://www.sterile.com

Microbiologics, Inc. - http://www.microbiologics.com

Nelson Labs - http://www.nelsonlabs.com

BD Diagnostic Systems - http://www.bd.com/ds/

Boston Analytical http://www.bostonanalytical.com/

MilliporeSigma  http://www.emdmillipore.com/

Charles River Microbial Solutions:  Endosafe, Accugenix & Celsis   - www.criver.com/micro

Avista Pharma Solutions  http://www.avistapharma.com

Associates of Cape Cod, Inc. - http://www.acciusa.com/


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The nature of this service is to provide a medium for communication.  The specific statements and endorsements of individuals participating in the discussions are not necessarily those of The Microbiology Network, Inc., the PMF, or the sponsors of the list.

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